Can I trade the same symbol using multiple strategies?

Kind of.

You can trade multiple routes but the symbol must be unique. So you CANNOT trade the same symbol using multiple strategies. But since Jesse strategies are merely Python classes, you can easily merge multiple strategies into one.

For example you can merge the entry signals, and exit signals of two strategies into one. However, you'd still be limited to one position at a time.

Use multiple sub-accounts on the same exchange

A good solution is to use multiple sub-accounts, one strategy per sub-account. This way you can even have one long and one short positions which is not normally possible.

Related: Can I run multiple instances of Jesse at the same time?